A friend of mine found a good way to use the Creuss in our last game. He put the Hil Colish on Mallice and sealed the system for everyone else. His own HS (we play Star by Star) was in an especially uncomfortable and useless and remote area of the galaxy. Using the four wormholes, plus (luck on his side, granted) two additional ones popped up by DS, plus the Wormhole Generator, he could virtually reach every point in the galaxy. Having the dimensional splicer ensured no one lingered in Wormholes. Decent strat, all in all. Putting Hil Colish in Mallice is a mandatory move, IMHO.
Mandatory, probably not. Highly recommended, definitely.