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Subject: Kary Mullis rss

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Amy Wiles
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Kary Mullis won the Nobel Prize for Chemistry in 1993 for inventing the polymerase chain reaction, or PCR. Molecular biologists wouldn't be able to do what we do without it, and the world would be a sadder and colder place.

Let me tell you a little about Dr. Mullis. After getting his Ph.D., he left science to write fiction, then ran a bakery for a couple years. A friend lured him back into biotech with a job offer, and he returned to California. At some point (perhaps during all of this) he dropped all the acid.

One night, after moving back to California to do SCIENCE, he went for a drive with his girlfriend along a windy road and envisioned PCR. He completely credits LSD for the idea, saying that if he'd never taken it, he probably wouldn't have had the idea. Shortly afterwards, his girlfriend dumped him. I guess it's hard being a genius.

Why am I telling you all this? Well, besides the apparent fact that dropping acid can win you the Nobel Prize. Because of something that Mullis said was not due to LSD. From Wikipedia, I present to you the following:

Wikipedia wrote:
Mullis writes of having once spoken to a glowing green raccoon. Mullis arrived at his cabin in the woods of northern California around midnight one night in 1985, and, having turned on the lights and left sacks of groceries on the floor, set off for the outhouse with a flashlight. "On the way, he saw something glowing under a fir tree. Shining the flashlight on this glow, it seemed to be a raccoon with little black eyes. The raccoon spoke, saying, ‘Good evening, doctor,’ and he replied with a hello." Mullis later speculated that the raccoon ‘was some sort of holographic projection and … that multidimensional physics on a macroscopic scale may be responsible’. Mullis denies LSD having anything at all to do with this.


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That's right, he's met Ch'p, and it's nothing to do with lysergic acid diethylamide. So Ch'p must be mentioned in lecture tomorrow when PCR is introduced.


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Andy Andersen
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I conger up stuff with rum and caffeine free diet Pepsi, but have had no Nobel prize nominations.

My congering is pretty lame
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David Kahnt
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It's fun, it's healthy, it's good exercise. The kids will just love it. And we put a little sand inside to make the experience more pleasant.
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You know, they say there was a man who jumped from the forty-FIFTH floor? But that's another story...
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That's not Ch'p...

This... this is Ch'p:



-DK
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Robert Wesley
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Maybe, it WAS PCP instead? whistle
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フィル
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Ashfield
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Pushing a lesbian old growth union-approved agenda since '94.
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Orangemoose wrote:
I conger up stuff with rum and caffeine free diet Pepsi, but have had no Nobel prize nominations.

My congering is pretty lame

Tell us how you really eel!
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Andy Andersen
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sbszine wrote:
Orangemoose wrote:
I conger up stuff with rum and caffeine free diet Pepsi, but have had no Nobel prize nominations.

My congering is pretty lame

Tell us how you really eel!

I eel just fine
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いい竹やぶだ!

South Euclid
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If LSD had been discovered in 1840 instead of 1940, Einstein would probably formulated his General Theory of Relativity ten years sooner.

But seriously, Watson and Crick's famous 1953 paper on the structure of DNA ended with one of the most eerily prescient statements in science:

“It had not escaped our attention that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.”
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いい竹やぶだ!

South Euclid
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sbszine wrote:
Orangemoose wrote:
I conger up stuff with rum and caffeine free diet Pepsi, but have had no Nobel prize nominations.

My congering is pretty lame

Tell us how you really eel!

"When the moon hit your eye
Like a big pizza pie—
That's a moray!"
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pronoblem baalberith
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I bought his Dancing Naked in the Mind Field the day it hit the shelves, a much anticipated book for me. I suggest you read it. Very funny stuff. I also suggest trying LSD/DMT to any person that is stable, without any metal health issues and of reasonable intelligence. It will change your life.

PCR is a huge discovery... much of the genome map and forensic DNA is due to PCR. If I remember correctly he described driving in the desert and having a rabbit run in front of his car... when tripping on LSD the image became of the rabbit somehow orbiting the car (running around the car as it traveled). This unlocked some mystery to the PCR puzzle for him. He did thank Albert Hoffman (LSD synthesis) at his prize ceremony.

He won the Japan Prize for the same thing prior to the Nobel. When greeted by the wife of the Japanese emperor he asked he if she knew any single Empresses. On return from the Japan or Nobel prize, I forget which, he met Bill Clinton and asked about his "did not inhale"...

Mullis was also a potential expert witness at the O.J. trial but neither side wanted to put him on the stand after they learned how unpredictable he was.



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いい竹やぶだ!

South Euclid
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That he won the Nobel for an idea he had only ten years previously shows just how important PCR is. Sad that since his Nobel Prize, Mullis has turned into a full-blown crank. He kind of followed Watson's lead there.
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Robert Wesley
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Re: Kary Mullis owed 'moi' around 350
Where is 'moi' *NOBEL PEACE PRIZE* for this? New UN Locale surprise
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EXTRA AVOCADO! Sonderegger
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BoardGameGeek » Forums » Everything Else » Chit Chat
Re: Kary Mullis
Came for the science, stayed because of the weird dc left-turn.
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Amy Wiles
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robigo wrote:
But seriously, Watson and Crick's famous 1953 paper on the structure of DNA ended with one of the most eerily prescient statements in science:

“It had not escaped our attention that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.”

As far as I understand it, that's because they'd figured out semi-conservative replication but didn't have any of the experimental evidence to demonstrate it yet. That'd be Meselson and Stahl in 1958.
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Rob
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pronoblem wrote:
I bought his Dancing Naked in the Mind Field the day it hit the shelves, a much anticipated book for me. I suggest you read it. Very funny stuff.


I just reserved it at my local library. Thanks for the recommendation!
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pronoblem baalberith
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Kary Mullis, Doc Ellis, and A Meditation on LSD
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Mr. Green
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The story of LSD itself is fascinating.
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pronoblem baalberith
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Sinister Dexter wrote:
pronoblem wrote:
I bought his Dancing Naked in the Mind Field the day it hit the shelves, a much anticipated book for me. I suggest you read it. Very funny stuff.


I just reserved it at my local library. Thanks for the recommendation!


I noticed that you italicized for me. I also went back an edited my post. I would have italicized it myself at the time but I posted that comment using my phone (subsequent posts on my PC) and with my calloused gorilla fingers I don't bother with any formatting, buttons, etc - just text.

I do not read many autobiographies but Dancing Naked in the Mind Field and Kitchen Confidential are my favorites. If you have any other suggestions for must read contemporary autobiographies / memoirs let me know... (besides A Heartbreaking Work Of Staggering Genius as that one is on deck)
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pronoblem baalberith
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LennyS wrote:
The story of LSD itself is fascinating.


Also: Acid Dreams: The Complete Social History of Lsd : The Cia, the Sixties, and Beyond ... the entire book is free online as HTML and PDF if you look around.

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Boo
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pronoblem wrote:
I also suggest trying LSD/DMT to any person that is stable, without any metal health issues and of reasonable intelligence. It will change your life.


Well that rules out me and half the population. I think the other half fails the "of reasonable intelligence" part.
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