Drizzt - Twinkle
Basically every turn I can avoid being damaged for 1? If the monster attack value is only 1 then I can totally avoided his damage?
No. You can only negate that damage from successful attacks from adjacent enemies.
Multiple monsters attack at ranged or the whole tile from the mushroom space. You cannot use Twinkle to prevent these attacks.
Multiple monsters deal damage on misses. You cannot prevent these either.