Just thought you'd like to know there is some info (although very mysterious info) at Fantasy Flight's website in the Rants section.
In his house at R'lyeh, dead Cthulhu waits dreaming
I hope they don't screw up the "you tell the story" part.
On the other hand a new setting is always welcome.
By the way: They moved the rant to an own design note page.
Some additional info in the Rants section today:
Other than raving about our latest Midnight book, I'm currently browbeating the graphic design for Runebound: Sands of Al-Kalim out of Schomburg . . . It's an expansion that I think provides a fun variant from the tried and true "level up and kick butt" strategy of Runebound. This one is much more heavily quest-based, making it (I hope) more roleplaying-intensive for those who like to blend their board game and roleplaying experiences. It also lets you focus on a particular strategy beyond simply what combat values to increase and what weapons to purchase, because the reward for each quest available to your character gives you special abilities. You might decide that your Hero needs a Legendary Mount so he can travel more easily through the punishing landscape of Al-Kalim; or you might wish to explore a Legendary Location to perfect your fighting skills against a specific type of foe; or perhaps you prefer to control the environment around you, so you quest for a Legendary Rune or Legendary Artifact.
Oh, and watch out for that sandstorm. It moves about the board of its own volition, and before you know it you might be trapped in the middle of the sucker ; ).