The ermine on the box is pictured with Anne of Brittany.
Quick research on Wikipedia:
It was the emblem of several dukes of Brittany.
The coat of arms of Brittany, ermine plain, was adopted by John III in 1316. Ermine had been used in Brittany long before, and there is no clue about its origin. It was probably chosen by the dukes because of its similarity with the French fleur-de-lis. The ermine, or stoat, as an animal became the badge of John IV at the end of the 14th century. It appeared later on numerous locations, including churches and castles. According to popular traditions, Anne of Brittany was hunting with her court when she saw a white ermine who preferred to die than to cross a dirty marsh. This episode would have inspired the duchess' motto : "Potius mori quam foedari" ("rather death than dishonour").