You want to play Feds, the Borg will be out in force, Klingons will be Lurking, the Dominion will be posturing and faction mixing is allowed.
The only rules are all the ships must be fed ships. Any thing else can be mixed.
My fleet at the moment is probably:
Resource: Flagship Independent (Dominion) (10)
U.S.S Excelsior (26)
Mr. Spock (5)
Montgomery Scott (5)
Li Nalas (3)
Quantum Torpedoes (6)
Transwarp Drive (3)
Ship SP: 57
U.S.S Yeager (22)
Mr. Spock (4)
Photon Torpedoes (4)
Ship SP: 33
Total Build SP: 100
Generated by STAW Builderhttp://www.dracossoftware.com/STAWHome.html
This is about as strong a Torpedo configuration as you can make.
The Yaeger in that configuration will spew out 4 or 5 hits every turn as long as its alive and can get a target lock. The extra movement of the ind dominion flagship should help position it to either get a hit, or avoid one in early game situations. Li Nalas and Lojour give the Excelsior 3 consecutive turns of quantums before having to reload. With the flagship for the TL, the free scan give BS via Spock. The Ship action can be used to activate Scotty for +2 dice. Lore may seem like a strange choice, but he can chew up disabled Lojur and Li Nalas as well as Scotty after he activates to make the first 3 volleys each hit for 9 potentially. Militia is there in case we don't get the scan to have BS and transwarp is to help facilitate torpedoes out the rear.