Randomly put the buildings in different spots for a change up?I'd say probably not... this is akin to those asking in Kingsburg to just bypass the rule on having to build left to right within each row... can throw off balance and make lower tiered buildings less valuable. FWIW, I wouldn't mind trying it this way just for the heck of it
I've been told there are scenarios in this game. I just assumed that non-standard building placement would be for those. Otherwise, I'm sure expansions can mix things up with alternative buildings.