Page 8, game setup
#3 Prepare the University: In every game, the white-bordered University Central tiles (Infirmary, Council Chambers, and Library) will be included somewhere in the University Board. The other rooms will be added randomly, depending on the number of player.
In the back, an optional setup involves drafting rooms, with the University Central tiles in a column as the core.
By saying these three tiles 'will be included somewhere in the University Board' suggests that they can be set up randomly as long as they are included in the mix of tiles that are in the board.