Dice Hate Me
The boardgame blog with worse luck than you! dicehateme.com
Couldn't you play this as a two player game if both players used two field researchers and doubled their starting resources? Maybe have an intern as well? It wouldn't be a perfect variant but I could see this being playable. You could even have one of the player's colors be a dominant color (so if it teams up with the other player they have final say in blend/research decision). Of course you would want to keep their score trackers separate so that way you could determine the order in which they are placed on the board.
It is certainly possible. We tinkered with some two-player ideas but ultimately wanted to publish the game without having to put too much on the players. It's something I'd love to revisit if we ever do a special version.
You are more than welcome to try - and if you discover an enjoyable variant please share it!