Ok guys, this one's just silly. I'm sure you've already done this before, but now you actually have a reason for it. Since Pokemon's just exploded so much lately, this is the most Pokemon-esque setup I could conceive. The villains are as "capturable" as you can get in this game. As usual, this uses a pretty diverse amount of sets.
Scheme: Secret Wars (so as to expose the Elite 4) Masterminds: Shiklah (Drasna) + Dr. Strange (Siebold) + Stryfe (Wikstrom) + Madelyne Pryor (Malva)
Adversaries: Monster Metropolis, Manhattan Earth 1610, (3) x-Men '92, (5) Skrulls Henchmen: Thor Corps., (4) Spider-Infected Allies: Groot (Grass), Human Torch/Ghost Rider (Fire), Nerkkod (Water), Electro (Pikachu), Time-Traveling Jean Grey (Mew), (5) Kraven (trainer) Special Rules: If Spider-Infected is included, it can only have special bystanders.