"Work as if you live in the early days of a better nation"
If you have some good cards in your tableau, a purge can be a great way of allowing you to play them again in coming turns.
One of my favorite "killer combos" is getting a political stooge (any ol' 1 rank will do) along with Dost Mohammed. When the purge comes you can pull Dost Mohammed back into your hand and then play him the next turn to immediately presence in 3/4 modes. He might be the strongest card in the game.
The number one mistake that new players make is that they don't fail topples when they should--usually convincing themselves that their chances of winning are better than they are. Once you start pulling Topples down frequently the game takes a different (and better) shape.