Some games like Betrayal at the House on the Hill rely on blank faces as part of a game mechanic, there needs to be zero faces on the dice. So I have no problem with that if there is a justifiable reason to have blank faces.
I haven't played that one. A lot of games use blanks in combat to mean a 'miss', which makes logical sense, but it's just not interesting. Anybody rolling blanks is just bored. Oh look I missed, I guess I just missed my turn. It seems like such a lazy game design to me.