More to the point... why would you want to?????????
I guess if you plan on playing the game only once in your lifetime, then maybe.
Honestly this is largely the motivation, the game rotation with my group is rough so unless the game really catches on it might only get played once or twice.
DO NOT use the modules on your first play. The game is a very full game without them and take a couple plays to fully get used to the gameplay.
And more inportantly, please experience the core gameplay like i intended it. Don't use any modules for at least a few games. Not because they're complicated, I believe you can handle them. Don't use them so that you can learn to appreciate the core before you replace parts of it.
Thanks for the advice. I'll leave them out.