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Subject: The Black Disease - revealed! rss

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AB
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An outbreak of the Black cube disease


or is it really an outbreak of:

Ebola [img]http://upload.wikimedia.org/wikipedia/commons/3/3f/Ebola_vir... [/img]An Electron micrograph of the filamentous structure of Ebola (courtesy of wikipedia)

Background
Caused by the Ebolavirus
Considered to be the deadliest virus of all time
~1000 nm in size (a pin head is about 2,000,000 nm in size)
Symptoms similar to malaria (fever, weakness & vomiting) and can result in internal and external bleeding
Outbreaks so far limited to mainly remote areas of the world
First reported to have emerged in 1976 (simultaneously in Sudan and Zaire)

Transmission

Ebola is highly contagious
Mostly transmitted through direct contact with infected bodily fluids
Possible spread by inhalation of airborne virus
No known reservoir of the disease
Human outbreaks traced back to contact with infected gorillas and chimpanzees, though Ebola is also lethal to primates

Death rate
As many as 90% of infected people are killed depending upon which type of Ebola is contracted

Cause of death

Organ failure and/or reduced blood volume with death occurring at 7-14 days

Treatment
Mostly supportive
Trial vaccines can be administered within 4 days of infection to help prevent death

Good news
Good hygiene practise can significantly reduce spread, so epidemics in developed countries is not likely
Spreads relatively slowly due to short infection time and transmission requires very close proximity
There is no symptomless carrying of this virus
The short period of infection and the high death rate tend to prevent outbreaks spreading too far
A vaccine has been developed that is 99% effective in Monkeys

Bad news
No officially recognised vaccine is available that is effective in humans
Potential Bioterrorist Agent (Ebola was considered by members of Japan's Aum Shinrikyo cult, Shoko Asahara led ~40 members to Zaire in 1992 under the guise of offering medical aid to Ebola victims, presumably this was an attempt to acquire samples of the virus)

[This is just for fun folks, sleep easy at night, its just a game...]
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Robert Rossney
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I love the part in The Hot Zone where Richard Preston is interviewing one of the infectious-disease specialists about how the disease is transmitted:

"If there were any significant airborne transmissibility to the disease, the situation would be much different."

"How so?"

"There would be a lot fewer of us."
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Galen Ciscell
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Cool! Have you identified the other three?

Galen
 
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Matt Fullenwider
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Blue looks like it could be Avian Influenza (H5N1).

http://en.wikipedia.org/wiki/H5N1

Red looks like it could be Smallpox.

http://en.wikipedia.org/wiki/Smallpox
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Zack Kinlaw
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Yellow appears to be Typhoid Fever.

http://en.wikipedia.org/wiki/Typhoid_fever
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John John
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"Hi, I won't be in for work today. I came down with a bad case of blue cubes."
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AB
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gciscell wrote:
Cool! Have you identified the other three?

Galen
The other three are a bit more ambiguous but I'd go with

Red - Smallpox

Yellow - Typhoid

Blue - Avian flu


AB
 
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Moisés Solé
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Seems right. Would be awesome if Zev chimed in.

I understand why real diseases are not mentioned in the rules, since this is a very sensitive topic. Naming made up diseases would severely distract from the atmosphere, so that option is out also.
 
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AB
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The only thing that might fit is the cell morphology on the cards. Things like the geography of the diseases is not accurate.

Maybe if the game was meant to be a simulation then naming the diseases would be worthwhile but as it isn't a simulation, I imagine its better to play it safe from Matt and Zev's point of view and stick with nice generic easily identifiable colours (simpler that way).

Also saves pedants from bashing the game saying how inaccurate the representation of smallpox epidemics are for example (given that the disease was eradicated from the world in the 1970's...)

AB
 
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Moisés Solé
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That's because our game is still going! hehehe.

Just curious if we are right. As I said, I understand, and believe it's the right thing, that no actual disease names are used.
 
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Chris Schenck
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I know this isn't consistent with the different pictures of the viruses on the cards, but I prefer to think of the 4 diseases as variations of the same base virus, as if some killer flu virus manifested itself in different ways as it spread across the various climates of the world. It's one disease, but it mutated rapidly and drastically into 4 different strains that require different cures.

That seems to be a more "believable" scenario than simultaneous massive outbreaks of 4 completely different and unrelated diseases across the world.



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Jon Badolato
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Considered to be the deadliest virus of all time


Minor point of contention with the above statement. Ebola is no doubt among the top few of viruses in lethality ONCE CONTRACTED, but it is certainly not among the deadliest viruses of all time as far as number of deaths attributed to it. That being said, I would rather suffer from yellow than black ! laugh
 
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Seth Jaffee
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Quote:
Red - Smallpox
I thought Red was supposed to be Sars...
 
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Enon Sci
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sedjtroll wrote:
Quote:
Red - Smallpox
I thought Red was supposed to be Sars...
Sars looks like a ring with hairs growing out of it.

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brian
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Hmmmm.... Not quite sold on the Avian flu. But the typhoid and small pox seem dead-on with the pics ont eh wikipedia site.
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AB
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jonb wrote:
Considered to be the deadliest virus of all time


Minor point of contention with the above statement. Ebola is no doubt among the top few of viruses in lethality ONCE CONTRACTED, but it is certainly not among the deadliest viruses of all time as far as number of deaths attributed to it. That being said, I would rather suffer from yellow than black ! laugh
Depends what you mean by deadliest I suppose. I was a bit vague but in terms of death rate as opposed to incidence its certainly not a very nice one.

AB
 
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AB
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sedjtroll wrote:
Quote:
Red - Smallpox
I thought Red was supposed to be Sars...
I guessed small pox over SARS for the same reason as Anarchosyn pointed out above.

AB

UPDATE: FWIW, after looking at a close up of the RED infection maybe SARS can't be ruled out so easily now I've had chance to see the infection card in better detail.


courtesy of BGG user:hrc333
 
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AB
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ColtsFan76 wrote:


Hmmmm.... Not quite sold on the Avian flu. But the typhoid and small pox seem dead-on with the pics ont eh wikipedia site.
Agreed, that was definitely the one I was least happy with too, at the end of the day it looks like a hell of a lot of things. I was going to suggest the Marburg virus but then as that isn't very well known so I thought Avian Flu would just be more memorable.

Transmission electron micrograph of the Marburg virus. Dr. Erskine Palmer, Russell Regnery, Ph.D., 1981. Public domain. Courtesy of wikipedia.org

AB
 
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Aron Fender
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I have been 'researching' this throughout my work day. I think that Blue is a representation of E. Coli - but it is so tough to tell. There are so many viruses that look like that picture.
 
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Randy Green
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Blue looks like Anthrax to me.

[url]
http://www.textbookofbacteriology.net/Anthrax.html[/url]
 
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Chris
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Marburg is alot like Ebola. Marburg also has the Sheppard's crook look to it as seen in the upper right hand corner of your image.
 
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Chris
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maelic001 wrote:
Blue looks like it could be Avian Influenza (H5N1).

http://en.wikipedia.org/wiki/H5N1

Red looks like it could be Smallpox.

http://en.wikipedia.org/wiki/Smallpox
kinkz1980 wrote:
Yellow appears to be Typhoid Fever.

http://en.wikipedia.org/wiki/Typhoid_fever
I agree with these they look right and geographically work
 
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Laura Appelbaum
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We played this for the first time last night, coincidentally after watching a show on Discovery Times on disgusting infectious diseases (the title was something like "Eaten Alive.") With this in mind, and looking at the locations, we decided the diseases were:

Red: devil SARS

Blue: soblue Lyme Disease (I don't know if they actually have this in Europe, but the North American prevalence made this the most likely choice after the Flu, but since there wasn't any blue in Asia where the flu usually originates, we went for Lyme. Could be West Nile Virus too, I guess).

Yellow: yuk Malaria or Typhus, no question.

Black:sauron Leishmaniasis (a disgusting, disfiguring skin infection spread by sand flies that lots of GIs fighting in Iraq [both wars] have gotten)



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Tomas Inguanzo
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Last Friday we played Pandemic following a game of Last Night on Earth, so I suggested that blue was zombie-ism. The humans won LNoE, but lost Pandemic. Twice. The triumphant valor of a handfull of rural hicks was all in vain, because the elite international medical team screwed up.
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Mike
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sauron Ebola
soblue avian flu
devil SARS or dengue
blush typhoid fever (malaria is less likely)

For malaria, see pictures of the flagellated male gamete form: http://www.impactmalaria.com/FR/EPS/Formations_et_cours_
internationaux/Formation_de_la_Liverpool_School_LSTMH/cours_liverpool/Unit_1/1_6_2.html

I don't understand the designer choice of typhoid fever. It is a bacterial disease for which there are two effective vaccines as well as antibiotic treatment. Typhoid fever will never cause a pandemic. Malaria is a better match geographically and clinically, but not picture-wise. On an annual basis, malaria kills about 5 times more people than all of the other diseases (above) combined.

Do you (dice geeks) know that for five families of viruses, their basic viral shapes are icosahedrons (d20):

Reoviridae (eg Colorado tick fever),
Picornaviridae (eg aseptic meningitis),
Togoviridae (eg encephalitis),
Herpesviridae (eg cold sores, etc, etc),
Papovaviridae (eg warts).




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