New York City
I'm wondering how a variant where each player is dealt 2 6 devs instead of start worlds would work. 2 6 devs and 6 other cards dealt at random. Discard 1 6 devs and 2 of the other 6 cards. Start with the other 6 dev in play and the remaining 4 cards is your starting hand. This sounds familiar so I'm sure someone has suggested it before.
Most of the 6-devs are rather specialized (e.g. GGP or GalRen). If you happen to draw a generalized one (e.g. TGuild or GalFed) you will likely annihilate your opponents.