Quoting myself on the solo rules as written:
I have just played my first two solo games.
Neither took longer than 15 minutes (including setup but excluding learning the rules).
It is important to note that solo play leans more towards the luck aspect than multiplayer because it removes some options.
The outcome of the game relies heavily on the luck of the role and the cards you draw.
I think it is fair to say that the luck involved is about as much as in Zombie in my Pocket. The available (game-defining) options are similar: Fight or try to evade.
Unlike in multiplayer once you have escaped a monster you do not have to face it again as you are in complete control of its movement.
It all comes down to risk management: "Do I think the reward for battling this monster is worth risking wounds?"
If this sounds like a negative review, that was not my intention!
Solo play is definitely enjoyable and difficult; my character died in both games.
But I dare say the game would not be worth its money if you bought it solely to play solitaire.