The rules for resolving dynamite seem to indicate that npc's are not effected since you roll your agility die.
Is this the case?. Seems a bit odd.
also what constitutes adjacent for dynamite? the shops next door?,station?,mine street?. also can the thrower get hurt since they have to be adjacent to use dynamite?
I believe these questions are answered in A Fistful o' Answers.
next question if you run out of npc's,equipmentghost rock or events do you reshuffle any or all or just carry on without.
I don't believe you reshuffle. Usually a game ends before the decks are completely out (especially since the end game conditions include them). Remember that the game ends based on what you rolled at the beginning OR if three conditions are met.
is a plastic used for the deputy like the sheriff?.
and is he effected by things like mine collapse if he happend to be there on the turn they occour like all the other npc's?
If you have an extra figure, you can certainly use it for the Deputy; just remember to move the figure along with the event card every turn as he travels. As mentioned in A Fistful o' Answers, the Deputy is a an event card, not an encounter card. Therefore, he cannot be affected by the mine collapse.