My wife and I play a lot of 2 player games and I, personally, am getting tired of the same occupations. Is there anything wrong with throwing in the 3+ or just using the 4+ occupations instead?
It's fine, but there are a few cards that are probably either too good or too terrible. Stonecutter, for example, I think would probably be too strong in 2er.
I don't play many 2er games, but we use most 4+ cards in our 3er games. We just talk about them and throw out the ones that are problematic.