"Destroy All Humans! is a video game franchise developed by Pandemic Studios, Locomotive Games, Sandblast Games and published by THQ. The two main protagonists are voiced by J. Grant Albrect and Richard Steven Horvitz, with the exception of the game Destroy All Humans! Big Willy Unleashed, in which actors Sean Donnellan and Darryl Kurylo portray the characters. The musical score for the series is performed by composer Garry Schyman. The first two games are available for the PlayStation 2 and Xbox game consoles while Big Willy Unleashed is only available for the Wii. The third installment, Path of the Furon first appeared for Xbox 360 on December 1, 2008 (NA) and February 6, 2009 on the Xbox 360 and PlayStation 3 (EU). All furons are named after viral or bacterial infections, or sometimes, the actual bacteria that cause the infections, such as Helicobacter, who is named after helicobacteria.
e games take place mostly on Earth where the Furon Cryptosporidium, also known as Crypto, is tasked by his superiors to gather Furon DNA locked inside human brain stems in order to save his race from cloning themselves into extinction. In the first game, Crypto's objectives also include investigating what happened to his previous clone. The second game features Crypto hunting for revenge, after the KGB try to assassinate him and successfully destroy the mothership and his mission officer, Orthopox, as well as exterminating the Furon enemy from the Martian War, the blisk. A spin-off for the Wii involves Crypto protecting Pox's new fast food chain using a giant robot mech disguised as the restaurant's mascot, called "Big Willy". The third game is available on Xbox 360 (and PlayStation 3 only in Europe and Australia), and involves Crypto seeking enlightenment to help him stop a conspiracy that threatens his empire. The first game takes place in 1959; the second game takes place in 1969; the Wii spin-off takes place in 1975 between the times of the second and third games; and the third in 1979."
Source: Wikipedia, "Destroy_All_Humans!_(series)", available under the CC-BY-SA License.